BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI)

The ARPA‑H solicitation (ARPA‑H‑SOL‑26‑149) seeks innovative health‑technology solutions that address critical gaps in the U.S. health‑care market, advance technology transition goals, and enable commercialization. Proposers must submit a two‑volume package. Volume I includes a cover page, an “Innovative Solutions Summary,” organization and point‑of‑contact details, award instrument (Other Transaction), performance period, team composition, and a detailed cost breakdown by Technical Area. An executive summary must describe the problem to be solved, the proposed approach, and anticipated benefits. If sub‑proposers are used, the prime must provide a cost/price analysis, competitive quotes (or a sole‑source justification), and CAGE codes. The solicitation also requires a comprehensive Technical Task Description (TDD) in Volume II that defines all tasks, sub‑tasks, locations, responsible organizations, deliverables (including IP assertions), human/animal‑subject considerations, and measurable milestones. Reporting obligations include an electronic technical status report within 90 days of award and periodic updates thereafter. Evaluation will be based on scientific and technical merit, proposer capability, relevance to the ARPA‑H mission and user experience, and cost realism. Unique requirements include explicit IP ownership tables (government purpose, unlimited or limited rights), representations regarding unpaid tax liabilities, cybersecurity and biosecurity compliance, and a mandatory cost realism analysis to ensure realistic budgeting aligned with the TDD. Successful proposals will demonstrate a clear path from research to market, a robust commercialization plan, and the ability to meet ARPA‑H’s transition and impact objectives.

Notice ID

5af8f100073345458dbdb604e4f9632c

Solicitation Number

ARPA-H-SOL-26-149

NAICS Code

541714

Classification Code

AN13