Synthesis of Self-Amplifying Nucleic Acid Constructs

**Subject: Synthesis of Self-Amplifying Nucleic Acid Constructs 1232SA26Q0044** This is a combined synopsis/solicitation (RFQ 1232SA25Q044) issued as a Request for Quotation for a service to generate five lipid nanoparticle encapsulated self-amplifying nucleic acid based on the genetic components of the alphavirus Venezuelan equine encephalitis virus (VEEV). This is a Total Small Business Set-Aside acquisition with a size standard of 19.0M. Offers must be submitted electronically and include detailed pricing, signatures, a valid SAM Unique Entity Identifier (UEI), acknowledgement of any amendments (SF-30), and active registration at SAM.gov. Quotes will be evaluated based on FAR 12.203, focusing on technical acceptability and fair and reasonable pricing (FAR 12.204). Offerors must provide a detailed explanation of their technical approach to meeting the Statement of Work (SOW) requirements, including experience on similar projects within the last five years, and must clearly identify any requirements in the SOW that cannot be successfully accomplished. The Government anticipates awarding a firm-fixed price requirements contract to the offeror representing the best value. Questions are due by January 5, 2026, at 4:00 PM Central Time.

Notice ID

7ccd0ceab6c44497800dd4c5806d2083

Solicitation Number

1232SA26Q0044

NAICS Code

541380

Classification Code

B529