Scalable Solutions Office (SSO) Mission Office Innovative Solutions Opening (ISO)

The Advanced Research Projects Agency for Health (ARPA‑H) is issuing Innovative Solutions Opening (ISO) solicitation ARPA‑H‑SOL‑24‑105, which invites solution summaries and full proposals for novel, high‑impact biomedical and health‑research ideas that cannot be pursued through traditional research or commercial pathways. The effort is organized into two phases with detailed task and sub‑task lists, and proposals must include a technical approach, milestones, intellectual‑property assertions, and, if applicable, human‑ or animal‑subject research descriptions. Submissions are accepted from academia, non‑profit, and for‑profit entities and will be awarded as Other Transaction (OT) agreements; multiple awards are anticipated. Proposers must submit all cost information in Excel spreadsheets, perform a cost/price analysis of any sub‑proposer offers, and provide competitive quotes or a short sole‑source justification when applicable. Required deliverables include a Solution Summary (cover page, project duration, resource‑sharing plan, team composition) and a full proposal (summary, goals, technical plan, management plan, bibliography). Evaluation will be based on scientific/technical merit, relevance to the ARPA‑H mission, proposer capabilities, and cost/price assessment. The solicitation remains open until 5 March 2029, and all submissions must be made through the ARPA‑H Solution Submission Portal, include the required certifications (e.g., no participation in malign foreign talent recruitment programs), and comply with the specified formatting and reporting requirements.

Notice ID

fb2f242ed53b4f8987e10c97ffbde88e

Solicitation Number

ARPA-H-SOL-24-105

NAICS Code

541715

Classification Code

AN13